Follow-up results of patients diagnosed with multicystic dysplastic kidney disease
Prognosis in patients with multicystic dysplastic kidney disease
Ümmühan Çay 1, Nilgün Çakar 2
1 Department of Pediatric Infection, Çukurova University Faculty of Medicine, Adana, 2 Department of Pediatric Nephrology, Ankara University Faculty of Medicine, Ankara, Turkey
DOI:10.4328/ECAM.10028 Received : 2021-03-01 Accepted : 2021-03-18 Published Online : 2021-04-16 Printed Online : 2021-05-01
Aim: Multicystic dysplastic kidney disease MCDKD is the second most common urinary system anomaly detected by prenatal USG and is probably one of the leading causes of having a single kidney in adults. When congenital kidney and urinary system anomalies are diagnosed in the intrauterine period and followed up and treated early in the postnatal period, the morbidity and mortality rates of the patients decrease and their quality of life increases. In this study, we aimed to evaluate the follow-up results of patients who were followed up with the diagnosis of MCDKD with prenatal and postnatal diagnosis, and to determine possible complications and their relationship with the prognosis.
Material and Method: In this study, 31 patients with MCDKD were examined. Nineteen patients were male (61.2%), 25 (77.41%) patients were diagnosed in the prenatal period. The cases, which were diagnosed in the prenatal or postnatal period but were included in the study according to the hospital file and outpatient card information, were evaluated retrospectively.
Results: MCDKD was detected on the left side in 18 patients (58.05%) and bilateral in one patient (3.2%). The follow-up period ranged from 7 days to 9 years. When the contralateral kidneys of the patients were examined, stage II hydronephrosis was found in two (6.6%), compensatory hypertrophy in 24 (80%) and the contralateral kidneys in 6 (20%) patients were found to be normal. It was found that hypertension developed in three (9.6%) patients and 15 (48%) patients had recurrent urinary tract infections during follow-up. Renal failure was detect-ed in only one patient with bilateral MCDKD, and the patient died.
Discussion: In conclusion, patients with MCDKD should be monitored with blood pressure, kidney function tests, urine analysis and USG at regular intervals. Early detection of complications such as hypertension, UTI, kidney failure, malignancy and appropriate treatment are important for the prognosis of the patients.
Keywords: Multicystic dysplastic kidney disease; Child; Follow-up; Result
Corresponding Author: Ümmühan Çay, Çukurova University Faculty of Medicine, Pediatric Infection Department, Adana, Turkey. E-Mail: email@example.com P: +90 5054940831 Corresponding Author ORCID ID: https://orcid.org/0000-0001-5803-878Xİ
How to cite this article: Ümmühan Çay, Nilgün Çakar. Follow-up results of patients diagnosed with multicystic dysplastic kidney disease. Eu Clin Anal Med 2021; 9(2): 11-14