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May 2022

Original Research

Determination the effect of meteorological changes in presentations to a pandemic hospital

The effect of meteorological changes in presentations to a pandemic hospital

Emine Emektar 1, Filiz Koç 2, Hüseyin Uzunosmanoğlu 1, Seda Dağar 1, Emine Fırat Göktaş 2

1 Department of Emergency Medicine, 2 Department of Infectious Diseases, Keçiören Training and Research Hospital, Ankara, Turkey

DOI:10.4328/ECAM.10029 Received : 2021-04-02 Accepted : 2021-05-24 Published Online : 2021-05-31 Printed Online : 2022-05-01

Abstract

Aim: Atmospheric pressure, air temperature, humidity, or sudden meteorological changes alter COVID-19 patient admissions. In the present study, we aimed to investigate the seasonal distribution of COVID-19 disease and its relationship with meteorological changes in our province, where the continental climate is dominant.

Material and Methods: This is a retrospective study. Patients who presented to our hospital’s pandemic outpatient clinic were enrolled. Patients’ time of presentation, the number of presentations and hospital outcomes were recorded. Daily meteorological data pertaining to the study period including air temperature, atmospheric pressure, humidity rate, amount of precipitation, and wind speed were obtained from the Directorate of Meteorology and recorded.

Results: During the 112-day study period, 11,898 patients presented to the pandemic outpatient clinic, and 2568 PCR (+) cases were detected. A total of 30 patients died during the study period. There was a significant positive correlation between the number of presentations and the mean temperature, humidity rate (p<0.05 for both). On the days free of restrictions, on the other hand, there was a significant negative correlation between the number of presentations and the mean temperature. There was a significant positive correlation between the
number of positive cases and the humidity rate both during the entire study period and on days when restrictions were not in effect (p<0.05 for both).

Discussion: We found a positive correlation between the number of presentations and the mean temperature, humidity rate; there was also a positive correlation between the number of positive cases and the humidity rate. Although the number of presentations was reduced on the days when the national restrictions were not in effect, we concluded that the restrictions did not affect the relationship between the number of patients and the meteorological parameters. Interactions between air pollution and meteorological factors may play a role in the transmission and pathogenesis of COVID-19, and multi-center prospective studies may provide a better insight into such interactions.

Keywords: Infection, COVID-19, Pandemic

Corresponding Author: Emine Emektar. Keçiören Training and Research Hospital, Department of Emergency Medicine, Ankara, Turkey Address: Pınarbaşı, Sanatoryum Caddesi Ardahan Sokak No:25, 06280 Keçiören/Ankara, Turkey. E-Mail: emineakinci@yahoo.com • P: +90 5055562675 • Corresponding Author ORCID ID: https://orcid.org/0000-0002-6056- 4401

How to cite this article: Emine Emektar, Filiz Koç, Hüseyin Uzunosmanoğlu, Seda Dağar, Emine Fırat Göktaş. Determination the effect of meteorological changes in presentations to a
pandemic hospital. Eu Clin Anal Med 2022; 10(2): 5-8

Evaluation of cardiology consultations for patients receiving Covid-19 treatment in pandemic wards

Evaluation of cardiology consultations for Covid-19

Gulay Aydın

Department of Cardiology, University of Health Sciences, Darica Farabi Education and Training Hospital, Kocaeli, Turkey

DOI:10.4328/ECAM.10030 Received : 2021-04-11 Accepted : 2021-05-12 Published Online : 2021-05-27 Printed Online : 2022-05-01

Abstract

Aim: The aim of this study was to investigate the reasons why cardiology consultation was requested from patients hospitalized to pandemic wards due to COVID-19 and what cardiac findings were obtained.

Materials and Methods: Fifty-eight consecutive patients over the age of 18 who were treated for COVID-19 in a pandemic ward were included in the observational retrospective study. The demographic features of the patients were recorded. Cardiac biomarkers on consultation such as D-dimer, high sensitive cardiac troponin T (hs-cTn), and N terminal pro B type natriuretic peptide (NT-pro BNP) were recorded. Electrocardiography (ECG) was taken. Pleural effusion and pericardial effusion were determined from thorax computed tomography
reports.

Results: In this study, we found the following findings in patients. The most common co-morbidity was hypertension (HT), which was detected in 35 (60.30%) patients. The most common reason for requesting consultation was ECG evaluation, which was the reason for cardiology evaluation in 45 (77.58%) patients. The most common ECG finding was atrial fibrillation that was found in 22 (37.90%) patients. The most common laboratory finding was an increase in d D-dimer levels in 44 (75.86%) patients. We detected 6 (10.34%) patients with non-ST segment
elevation myocardial infarction (Non-STEMI), and anti-ischemic therapy was initiated. Pulmonary embolism was detected in 1 (1.72%) patient, and anticoagulant therapy was initiated. Four (6.80%) patients had acute pericarditis with pericardial effusion, and colchicine and steroid therapy were initiated.

Discussion: Therefore, COVID-19 patients who were followed in the pandemic ward should be evaluated by the cardiologist to investigate cardiac effects due to COVID-19 infection.

Keywords: COVID-19, Cardiology, Consultation

Corresponding Author: Gulay Aydin, Department of Cardiology, SBU Farabi Education and Training Hospital, Fevzicakmak Neighborhood, Dr. Zeki Acar Street. No:62, 41700 Darica, Kocaeli, Turkey. E-Mail: drgulayaydin@gmail.com • P: +90 262 655 43 45 • F: +90 262 655 21 71 • Corresponding Author ORCID ID: https://orcid.org/0000-0002-3151-44448

How to cite this article: Gulay Aydin. Evaluation of cardiology consultations for patients receiving Covid-19 treatment in pandemic wards. Eu Clin Anal Med 2022; 10(2): 9-11

Comparative effects of hypertonic solutions and pentoxifylline in sepsis

Sepsis

Yuksel Dogan 1, Dilek Burukoğlu 2, Cengiz Baycu 3, Tarik Caga 4, Mehlika Bilgi Kırmacı 5

1 Department of General Surgery, Bartın State Hospital, Bartın, 2 Department of Histology and Embriyology, Osmangazi University, Eskişehir, 3 Department of Histology and Embriyology, Okan University, İstanbul, 4 Department of General Surgery, Osmangazi University, Eskişehir, 5 Department of General Surgery, Afyonkarahisar University, Afyonkarahisar, Turkey

DOI:10.4328/ECAM.10034 Received : 2022-01-24 Accepted : 2022-04-23 Published Online : 2022-04-23 Printed Online : 2022-05-01

Abstract

Aim: Evaluation of the effects of hypertonic solutions and pentoxifylline treatments on the sepsis model.

Material and Methods: Thirty-two Sprague-Dawley rats were used. Experimental sepsis was induced by cecal ligation and puncture in all rats. At the end of the septic shock period, animals were divided into four groups, including eight rats per group, according to the treatment received as follows: sham (cannulation only, sepsis and no resuscitation), HS (3% NaCl 10 ml/kg/hr) and PTX (6 mg/kg/hr) and HS+PTX. Twenty-four hours of resuscitation after surgery, the rats were relaparotomized. Blood obtained from the heart for hematologic parameters and tissue samples (liver, lung and ileum) were collected for histopathologic analysis. The body temperature of the animals was obtained throughout the end of the experiment. Mortality rates in all groups were evaluated and compared.

Results: To assess the effects of hypertonic solutions and pentoxifylline on treating sepsis, the leukocyte, platelets and PMN values were compared. There was a significant difference between the HS Group, and PTX Group (p<0,05). However, there was no difference between the control Group (C) and HS+PTX Group (p>0.05). When fever values were compared, there was a meaningful difference between the control Group (C) and HS+PTX Group. Histopathological findings of liver, ileum and lung were compared and there was no difference between the HS Group and the PTX Group (p>0.05); but there was a significant difference between the control Group (C) and HS+PTX Group (p<0,05). The mortality rate of HS +PTX was evaluated within 24 hours, and rates of 25%, 37%, 50% and 25% were determined.

Discussion: We found Hypertonic solutions and pentoxifylline useful in the treatment of sepsis. According to the hematologic and histopathologic assessments and the evaluation of the mortality rates, early co-administration of hypertonic solutions and pentoxifylline reduces the incidence of mortality and morbidity due to septic qlinique. It is a preventive and protective method for reducing the response. Although the experimental data are positive and the rationale for the use of hypertonic solutions in the care of patients in sepsis is reasonable, many clinical studies need the safety and efficacy of sepsis treatment.

Keywords: Sepsis, Hypertonic, Pentoxifylline 

Corresponding Author: Yuksel Dogan, Department of General Surgery, Bartın State Hospital, Bartın, Turkey. E-Mail: ydogan49@yahoo.com.tr • P: +90 533 453 49 35 • Corresponding Author ORCID ID: https://orcid.org/0000-0002-0000-4664

How to cite this article: Yuksel Dogan, Dilek Burukoğlu, Cengiz Baycu, Tarik Caga, Mehlika Bilgi Kırmacı. Comparative effects of hypertonic solutions and pentoxifylline in sepsis. Eu Clin Anal Med 2022; 10(2): 12-16