May 2024
Original Research
B12 deficiency in children in Karabük city prevalence and key health insights
B12 vitamin deficiency study with large-scale dataset
Yusuf Deniz, Burak Demircioğlu, İrem Kuter Emeklioğlu
Department of Pediatrics, Faculty of Medicine, Karabuk University, Training and Research Hospital, Karabuk, Turkey
DOI: 10.4328/ECAM.10084 Received: 2024-04-04 Accepted: 2024-04-29 Published Online: 2024-04-29 Printed Online: 2024-05-01 Eu Clin Anal Med 2024;12(2):18-21
Abstract
Aim: The primary objective of this study was to investigate the prevalence and characteristics of vitamin B12 deficiency among pediatric individuals residing in the Karabük region, with the aim of highlighting the significance of raising awareness and formulating effective management strategies to address this health concern.
Material and Methods: The medical records of children under 18 who came to Karabük University Faculty of Medicine Training and Research Hospital in 2022 were retrospectively reviewed. Information such as B12 levels, demographic details, and blood parameters were examined using SPSS software.
Results: Out of 6133 children in the study, 1847 cases showed B12 deficiency or borderline deficiency. The prevalence of B12 deficiency was 4.5%, with 25.59% of children having borderline B12 levels. Children with B12 deficiency had a mean age of 11 years, and females had a higher prevalence in all age groups. Significant relationships were found between gender, age, and B12 levels.
Discussion: In this study, it is revealed that many children in Karabük province suffer from vitamin B12 deficiency. This emphasizes the pressing need for more awareness and effective strategies to address B12 deficiency in children, especially in the pediatric population. It is highlighted that promoting vitamin B12, along with iron and vitamin D, in public health programs is crucial. More research and specific healthcare policies are necessary to tackle this issue successfully.
Keywords: Vitamin B12 Deficiency, Children, Prevalence, Management Strategies, Hematological Parameters
Corresponding Author: Yusuf Deniz, Department of Pediatrics, Faculty of Medicine, Karabuk University, Training and Research Hospital, Karabuk, Turkey. • E-Mail: ydeniz123@hotmail.com • P: +90 507 381 55 44 • Corresponding Author ORCID ID: https://orcid.org/0000-0003-3684-2421
Other Authors ORCID ID: Burak Demircioğlu, https://orcid.org/0000-0001-8670-5519 • İrem Kuter Emeklioğlu, https://orcid.org/0000-0002-0167-5451
This study was approved by the Ethics Committee of Karabük University (Date: 2023-12-07, No: 2023/1566)
How to cite this article: Yusuf Deniz, Burak Demircioğlu, İrem Kuter Emeklioğlu. Article B12 deficiency in children in Karabük city prevalence and key health insights. Eu Clin Anal Med 2024;12(2):18-21
This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of the license, visit https://creativecommons.org/licenses/by-nc/4.0/
The relationship of CURB65-L and CURB65-LC (lactate clearance) with mortality in pneumonia patients admitted to the emergency department
CURB65, lactate and pneumonia
Birsen Ertekin 1, Tarık Acar 1, Alpay Tuncar 2, Azmi Eyiol 3
1 Department of Emergency, University of Health Sciences, Beyhekim Training and Research Hospital, Konya, 2 Department of Emergency, Ankara Etlik City Hospital, Ankara, 3 Department of Cardiology, University of Health Sciences, Beyhekim Training and Research Hospital, Konya, Turkey
DOI: 10.4328/ECAM.10086 Received: 2024-04-06 Accepted: 2024-04-29 Published Online: 2024-04-30 Printed Online: 2024-05-01 Eu Clin Anal Med 2024;12(2):22-26
Abstract
Aim: The study aims to examine the correlation between lactate, lactate clearance, CURB-65, CURB65-L, and CURB65-LC scores with mortality in pneumonia patients who were admitted to the emergency department.
Material and Methods: A total of 123 patients diagnosed with pneumonia who applied to the emergency department were assessed prospectively. Lactate clearance (%): [lactate at admission – lactate at 24th hour / lactate at admission) × 100]. Statistical comparisons were made across patient groups based on lactate, lactate clearance, and CURB-65 scores. These groups included survivors and non-survivors, patients in the intensive care unit and those who were not, patients receiving mechanical ventilation and vasopressor support, and those who did not, as well as patients with a hospital stay ≤10 days and those with a hospital stay > 10 days.
Results: Among patients with severe illness who did not survive and required intensive care unit admission, mechanical ventilation and vasopressor support, the lactate and CURB-65 scores were significantly higher, while the lactate clearance score was lower (p < 0.001 for all). The predictive power of CURB65-L and CURB65-LC for mortality was determined to be higher than CURB-65 and lactate clearance alone (AUC: 0.904, 0.855, 0.783, 0.834, respectively) (p<0.001 for all).
Discussion: The presence of lactate, the CURB-65 score, and lactate clearance level assessed upon admission to the emergency department can serve as predictors of negative results in patients with pneumonia. In addition, the combination of CURB65-L and CURB65-LC enhances the predictive power of CURB-65 and LC individually in determining mortality.
Keywords: Lactate, Lactate Clearance, CURB-65, CURB65-L, CURB65-LC
Corresponding Author: Birsen Ertekin, Department of Emergency, University of Health Sciences, Beyhekim Training and Research Hospital, Konya, Turkey. • E-Mail: biceacil@hotmail.com • P: +90 543 849 59 64 • Corresponding Author ORCID ID: https://orcid.org/0000-0002-0630-8634
Other Authors ORCID ID: Tarık Acar, https://orcid.org/0000-0002-1131-4027 . Alpay Tuncar, https://orcid.org/0000-0002-3889-819X . Azmi Eyi̇ol, https://orcid.org/0000-0003-2740-1966
This study was approved by the Ethics Committee of Necmettin Erbakan University, Faculty of Medicine (Date: 2023-06-16, No: 2023/4378(14509))
How to cite this article: Birsen Ertekin, Tarık Acar, Alpay Tuncar, Azmi Eyiol. The relationship of CURB65-L and CURB65-LC (lactate clearance) with mortality in pneumonia patients admitted to the emergency department. Eu Clin Anal Med 2024;12(2):22-26
Retrospective analysis of patients involved in intensive care for poisoning and received extracorporal treatment
Extracorporal treatment in poisoning
Muhammed Kamiloğlu 1, Ramazan Köylü 1, Öznur Köylü 2, Fatih Emin Vişneci 1, Nazire Belgin Akıllı 1, Ozan Özelbaykal 1
1 Department of Emergency Medicine, 2 Department of Biochemistry, Health Sciences University, Konya Training and Research Hospital, Konya, Turkey
DOI: 10.4328/ECAM.10087 Received: 2024-04-19 Accepted: 2024-04-30 Published Online: 2024-04-30 Printed Online: 2024-05-01 Eu Clin Anal Med 2024;12(2):27-32
Abstract
Aim: We planned to examine patients who presented to the emergency department with poisoning and were followed up in intensive care in terms of extracorporeal treatment.
Material and Methods: The study was conducted retrospectively. Patients who were admitted to the emergency department due to poisoning between 2008 and 2018 and were followed up in intensive care and received extracorporeal treatment were included in the study.
Results: 152 patients were included in the study. The median age of the included patients was 37.5 years. 88 (57.9%) of the patients were women and 64 (42.1%) were men. Of the patients participating in the study, 52 (34.2%) were on mushrooms, 29 (19.1%) were on antiepileptics, 16 (10.5%) were on methanol-ethylene glycol, 9 (6%) were on antihypertensives, and 7 were on antihypertensives. (4.5%) were tricyclic antidepressants, 6 (3.9%) were lithium, 5 (3.3%) were opioids, 3 (2%) were organophosphates, 3 (2%) were digoxin, 3 (2%) were monitored for theophylline, 3 (2%) for oral anti-diabetic, 3 (2%) for aspirin, and 3 (2%) for paracetamol. 35 (23%) required mechanical ventilation, 24 (15.8%) developed CKD after extracorporeal treatment, 20 (13.1%) developed multiorgan failure, and 20 (13.1%) developed in-hospital mortality.
Discussion: It was determined that the data we obtained were compatible with the existing literature when considering the studies in the literature and current intensive care patient evaluation criteria.
Keywords: Extracorporeal, Intensive Care, Emergency Roo, Poisoning
Corresponding Author: Muhammed Kamiloğlu, Department of Emergency Medicine, Health Sciences University, Konya Training and Research Hospital, 42080, Konya, Turkey. • E-Mail: drfather@hotmail.com • P: +90 332 257 06 06 • Corresponding Author ORCID ID: https://orcid.org/0000-0003-0317-018X
Other Authors ORCID ID: Ramazan Köylü, https://orcid.org/0000-0002-7685-8340 . Öznur Köylü, https://orcid.org/0000-0002-6888-6309
Fatih Emin Vişneci, https://orcid.org/0000-0001-8050-4433 . Nazire Belgin Akıllı, https://orcid.org/0000-0001-9329-0964 . Ozan Özelbaykal, https://orcid.org/0000-0002-1112-3183
This study was approved by the Ethics Committee of Necmettin Erbakan University, Meram Faculty of Medicine Research on Non-Pharmaceutical and Medical Devices Ethics Committee (Date: 2018-06-01, No: 2018/1400)
How to cite this article: Muhammed Kamiloğlu, Ramazan Köylü, Öznur Köylü, Fatih Emin Vişneci, Nazire Belgin Akıllı, Ozan Özelbaykal. Retrospective analysis of patients involved in intensive care for poisoning and received extracorporal treatment. Eu Clin Anal Med 2024;12(2):27-32
Case Report
Churg-Strauss syndrome: A case report
Case presentation
Elif Açar 1, Orhan Kayakıran 2, Suat Konuk 2, Emine Özsarı 2
1 Department of Allergy-Immunology, Kayseri Erciyes University Hospital, Kayseri, 2 Department of Pulmonology, Abant Izzet Baysal University Hospital, Bolu, Turkey
DOI: 10.4328/ECAM.10082 Received: 2023-12-26 Accepted: 2024-04-22 Published Online: 2024-04-27 Printed Online: 2024-05-01 Eu Clin Anal Med 2024;12(2):33-35
Abstract
Churg-Strauss Syndrome, currently referred to as Eosinophilic Granulomatosis with Polyangiitis, is a multisystemic disease characterized by asthma and eosinophilia. Diagnostic criteria include Asthma, Abnormalities in the paranasal sinuses, Eosinophilia > 10%, Neuropathy (mono or poly), Pulmonary infiltrates, and Biopsy with vessel involvement containing extravascular eosinophilia. EGPA, which can be confused with many other diseases, should always be considered in the differential diagnosis in the presence of asthma and eosinophilia. In this case, we discussed Churg-Strauss disease diagnosed in a 43-year-old male patient.
Keywords: EGPA, Asthma, Eosinophilia
Corresponding Author: Orhan Kayakıran, Department of Pulmonology, Abant Izzet Baysal University Hospital, Bolu, Turkey. • E-Mail: orhankayakiran.7@gmail.com • P: +90 538 236 10 11 • Corresponding Author ORCID ID: https://orcid.org/0000-0001-8419-7039
Other Authors ORCID ID: Elif Açar, https://orcid.org/0000-0002-4669-5034 • Suat Konuk, https://orcid.org/0000-0002-8240-4775 • Emine Özsari, https://orcid.org/0000-0001-5842-7849
How to cite this article: Elif Açar, Orhan Kayakıran, Suat Konuk, Emine Özsarı. Churg-Strauss syndrome: A case report. Eu Clin Anal Med 2024;12(2):33-35